These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Differences in some behavioural effects of deprenyl and amphetamine enantiomers in rats.
    Author: Timár J, Gyarmati Z, Barna L, Knoll B.
    Journal: Physiol Behav; 1996 Aug; 60(2):581-7. PubMed ID: 8840922.
    Abstract:
    Effects of deprenyl and amphetamine enantiomers on different behavioural patterns were compared. Whereas (+)-amphetamine in doses of 1-3 mg/kg SC, (-)-amphetamine, and (+)-deprenyl in doses of 5-20 mg/kg SC increased the locomotor activity and the time the animals displayed stereotyped head movement, enhanced the acquisition of conditioned avoidance responses, and developed positive place preference conditioning, (-)-deprenyl, even in as high a dose as 20 mg/kg SC, failed to show any amphetamine-type behavioural effect. The results provide further proof why (-)-deprenyl, in contrast to other members of the amphetamine family, can be considered as a safe drug.
    [Abstract] [Full Text] [Related] [New Search]