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  • Title: Genetic polymorphisms of red cell enzymes in tribes of Andhra Pradesh, India.
    Author: Naidu JM, Babu BV, Yasmin, Devi SS.
    Journal: Gene Geogr; 1995 Apr; 9(1):7-14. PubMed ID: 8845341.
    Abstract:
    The genetic heterogeneity of some common red cell enzyme markers among four endogamous tribal populations namely Konda Dora, Kotia, Bod Mali and Manzai Mali was investigated by starch/polyacrylamide/cellulose acetate gel electrophoresis. ACP, ESD, PGM1, G6PD, AK1, ADA, 6PGD enzymes and haemoglobin exhibited a polymorphism. PGM2, LDH, MDH, SOD, GOT, CA1, CA2 and GPI were monomorphic. A slow variant of SOD similar to that found in SOD 2-1 heterozygote was observed with a frequency of 1.31% among Kotia tribe. Most populations of the present study were in Hardy-Weinberg equilibrium for the majority of the genetic markers examined. The results are discussed in the light of available data on other Andhra populations.
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