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  • Title: [Intra-arterial infusion chemotherapy for breast cancer].
    Author: Matsumoto Y, Terakado H, Ikawa M, Hamada E, Watanabe Y, Nakasato S, Takaki S, Murata M, Miura T.
    Journal: Gan To Kagaku Ryoho; 1996 Sep; 23(11):1526-8. PubMed ID: 8854797.
    Abstract:
    In order to reduce toxic effects while attaining maximal therapeutic effects, epirubicin 10 mg/day, cyclophosphamide 100 mg/day and prednisolone 10 mg/day were administered through in indwelling catheter inserted into the internal mammary artery and/or subclavian artery for 3-4 weeks, employing the implantable port system for the treatment of unresectable breast cancer and recurrent cancer. Ten out of 11 patients (91%) with unresectable breast cancer showed a response (CR 3, PR 7, NC 1) to this modality of intra-arterial infusion chemotherapy. Seven out of 11 patients (64%) with recurrent cancer of the breast showed a response (CR 1, PR 6, NC 4). Intraarterial infusion chemotherapy for the unresectable advanced breast cancer and recurrent breast cancer proved to be an effective modality of treatment.
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