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  • Title: Methotrexate treatment of Wegener granulomatosis in children.
    Author: Gottlieb BS, Miller LC, Ilowite NT.
    Journal: J Pediatr; 1996 Oct; 129(4):604-7. PubMed ID: 8859270.
    Abstract:
    Wegener granulomatosis traditionally has been treated with glucocorticoids and cyclophosphamide. Both the disease and its treatments are associated with significant morbidity and mortality rates. There has been an effort to find effective but less toxic alternative treatments. We describe three children with Wegener granulomatosis who responded well to treatment with glucocorticoids and methotrexate, similar to a regimen used in adults.
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