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PUBMED FOR HANDHELDS

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  • Title: Epidermolysis bullosa dystrophica of Hallopeau-Siemens and squamous-cell carcinoma: a case report.
    Author: Van Rengen A, Degreef H.
    Journal: Dermatology; 1996; 192(4):418-9. PubMed ID: 8864399.
    Abstract:
    A 46-year-old patient suffering from Hallopeau-Siemens type epidermolysis bullosa dystrophica presented a large squamous-cell carcinoma of the left hand. No metastases were observed. The tumour was resected and the phalanxes were amputated. The wound was covered with autologous skin grafts. Squamous-cell carcinoma is extremely aggressive in these patients and surgery is the only effective therapy. This life-threatening complication should always be kept in mind and a biopsy taken of every chronic, non-healing ulceration and of each atypical lesion.
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