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  • Title: Embolic stroke in a pregnant patient with a mechanical heart valve on optimal heparin therapy.
    Author: Watson WJ, Freeman J, O'Brien C, Benson M.
    Journal: Am J Perinatol; 1996 Aug; 13(6):371-2. PubMed ID: 8865984.
    Abstract:
    A 28-year-old woman with a mechanical aortic heart valve experienced an embolic stroke in early pregnancy after her anticoagulation therapy was changed from warfarin to heparin. This occurred despite use of a subcutaneous heparin infusion pump and optimal anticoagulation. Thromboembolism can occur in pregnant patients with mechanical heart valves despite optimal heparin therapy.
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