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  • Title: [Features of noradrenaline stimulation of rat liver mitochondria respiration by ADP and calcium ions].
    Author: Stefankiv IuS, Babskyĭ AM, Shostakovska YV.
    Journal: Ukr Biokhim Zh (1978); 1995; 67(6):22-7. PubMed ID: 8867307.
    Abstract:
    A single administration of a physiological dose of noradrenaline to animals. in contrast to adrenaline, stimulates the respiration of mitochondria not only under oxidation of FAD-dependent Krebbs cycle substrate of the succinase but also HAD-dependent substrate of alpha-ketoglutarate. In the both cases the phosphorylation rate increases, since the action of noradrenaline, separating the respiration and oxidative phosphorylation, was not found. Noradrenaline increases the capacity of mitochondria to more actively absorb calcium ions under oxidation of succinate than under that of alpha-ketoglutarate.
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