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  • Title: [Initial manifestations and late diagnosis in chronic atrophic polychondritis: apropos of a series of 15 patients].
    Author: Brouillard M, Louville A, Gillot JM, Tillie I, Delaporte E, Houvenagel E, Hatron PY, Decoulx M, Hachulla E, Piette F, Tonnel AB, Devulder B.
    Journal: Rev Med Interne; 1996; 17(7):541-4. PubMed ID: 8881378.
    Abstract:
    An auricular or nasal chondritis or a saddle nose deformity are the initial manifestation in half of cases of relapsing polychondritis; the other initial manifestations are various and less evocative; polyarthritis, laryngo-tracheal symptoms, episcleritis which delay the diagnosis. From 15 cases of relapsing polychondritis, the diagnosis time from the first symptom are studied; this one is long, about 3 years and 6 months (from 3 months to 17 years) in 13/15 of the cases even if the first manifestation is typical (external chondritis). In two cases only, the diagnosis was established after the first attack. This late of diagnosis had socioeconomical impact and exposed to severe complications like tracheal chondritis.
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