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  • Title: Electron microscopic study of GABAergic synaptic innervation of neurotensin-immunoreactive neurons in the dorsal raphe nucleus.
    Author: Wang QP, Guan JL, Nakai Y.
    Journal: Brain Res; 1996 Aug 19; 730(1-2):118-24. PubMed ID: 8883895.
    Abstract:
    A double immunocytochemical method combining the preembedding avidin-biotin-peroxidase-complex technique and the postembedding immunogold technique was used to examine synaptic interactions between GABAergic and neurotensin-containing neurons in the same tissue sections of the dorsal raphe nucleus of the rat. Whereas the neurotensin-like immunoreactive perikarya rarely received synapses from GABA-like immunostaining axon terminals, the neurotensin-like immunoreactive dendrites frequently received synapses from GABA-like immunoreactive neurons. These results suggest that GABAergic neurons could modulate neurotensinergic neurons in the dorsal raphe nucleus through synaptic relations. The immunocytochemically identified local synaptic circuit in the dorsal raphe was discussed.
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