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  • Title: [May Perthes' disease be due to venous block? Experimental investigations on growing pigs].
    Author: Schulitz KP, Dustmann HO, Sinn H.
    Journal: Z Orthop Ihre Grenzgeb; 1977 Jun; 115(3):299-304. PubMed ID: 888516.
    Abstract:
    In 13 growing pigs (mini-pigs) all veins draining the head of femur were ligated intra-abdominally. In 2 i.v. injection of 12% Varigloban into the common iliac vein was added, in another 2 the same drug was injected into the head of femur. No real changes could be seen in X-rays, macro- and microscopically. Slides showed only more or less pronounced fibrosis. Scintigrams showed a reduction of radio-active storage in the head of femur by about 12%. The results and conclusions for human pathology are discussed.
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