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  • Title: Liver transplantation in Italy: preliminary 10-year report. The Monotematica Aisf-Olt Study Group.
    Author: Fagiuoli S, Leandro G, Bellati G, Gasbarrini A, Rapaccini GL, Pompili M, Rendina M, De Notariis S, Francavilla A, Gasbarrini G, Ideo G, Naccarato R.
    Journal: Ital J Gastroenterol; 1996; 28(6):343-50. PubMed ID: 8891851.
    Abstract:
    Experience in liver transplantation (OLT) in Italy over a ten-year period is reported. Data were obtained using a multiple-items form collected from Italian liver transplant centres (reference centres) and other Italian institutions actively involved both in the processes of evaluation of the candidates and the follow-up of liver transplant recipients (afference centres). During this period, a total of 1046 liver transplants were performed on 954 patients, with a cumulative proportional survival of 71%. The most common indication for liver transplantation was post-hepatitic cirrhosis due to either hepatitis B virus (+/-hepatitis Delta virus) or hepatitis C virus infection. Good survival rates were observed, particularly in controversial indications, such as alcoholic cirrhosis, post-hepatitic hepatitis B virus-related cirrhosis and hepatocellular carcinoma, most likely due to proper and careful selection of the patients. Cirrhosis, secondary to an autoimmunity-based liver disease, showed the highest rate of rejection episodes. Infections, in our study population, were the most common cause of death after transplantation.
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