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  • Title: Immunoresponsiveness of fast-growing chickens as influenced by feeding regimen.
    Author: Praharaj NK, Gross WB, Dunnington EA, Nir I, Siegel PB.
    Journal: Br Poult Sci; 1996 Sep; 37(4):779-86. PubMed ID: 8894222.
    Abstract:
    1. Immunoresponsiveness and disease resistance were measured in broiler males maintained on ad libitum feeding throughout or on alternate-day feeding. Alternate-day restrictions were started 1 and 2 d after hatch so that on any one day there were chicks fed and fasted. 2. Severity of response to E. coli challenge as measured by lesion scores, and mortality was greater for chicks fed ad libitum than those fed on alternate days. For chicks fed on alternate days, lesion scores were lower for those without access to feed for the 24-h period immediately after challenge. 3. Spleen weights, the indicator of response to marble spleen disease virus challenge, were higher for chicks fed ad libitum than those fed on alternate days. 4. Antibody response to sheep red blood cell antigen was not affected by feeding regimen. 5. Ratios of heterophils to lymphocytes were higher for chicks given access to feed for the previous 24-h period than for those fasted during the previous 24-h or those that had been fed ad libitum. 6. Results of this experiment suggest that for alternate-day feeding programs, vaccination be administered on the day that chicks are not fed.
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