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  • Title: Intravenous immunoglobulin therapy for refractory myositis.
    Author: Moriguchi M, Suzuki T, Tateishi M, Hara M, Kashiwazaki S.
    Journal: Intern Med; 1996 Aug; 35(8):663-7. PubMed ID: 8894745.
    Abstract:
    The efficacy of polyvalent intravenous immunoglobulin therapy (IVIG) was evaluated in three patients with refractory myositis. Patients refractory to conventional therapy, such as corticosteroid administration, corticosteroid or cyclophosphamide pulse therapy [2 with dermatomyositis (DM), 1 with polymyositis (PM)] were treated with IVIG (0.4 g/kg daily) for 5 days. Clinical improvement was apparent within 1-2 months after IVIG and persisted for 19-23 months (DM patients) and 12 months (PM patient). No adverse effects were observed. Thus, IVIG may be considered an effective therapy for refractory myositis.
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