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  • Title: Specificity of IS6110-based amplification assays for Mycobacterium tuberculosis complex.
    Author: Hellyer TJ, DesJardin LE, Assaf MK, Bates JH, Cave MD, Eisenach KD.
    Journal: J Clin Microbiol; 1996 Nov; 34(11):2843-6. PubMed ID: 8897197.
    Abstract:
    The specificity of IS6110 for the Mycobacterium tuberculosis complex has recently been questioned. We observed no cross-reaction with 27 nontuberculous mycobacteria using strand displacement- and PCR-based amplification of the nucleotide 970 to 1026 and 762 to 865 regions of IS6110. These data support use of selected regions of IS6110 as M. tuberculosis complex-specific targets.
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