These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Systemic hypoxia facilitates somato-cardiac sympathetic A- and C-reflexes in anesthetized rats.
    Author: Li WM, Sato A, Suzuki A, Trzebski A.
    Journal: Neurosci Lett; 1996 Oct 04; 216(3):175-8. PubMed ID: 8897486.
    Abstract:
    In rats anesthetized with urethane, electrical stimuli applied to tibial nerve afferents produced a somato-sympathetic A-reflex of 41 +/- 2 (mean +/- SEM)ms latency and C-reflex of 210 +/- 13 ms latency recorded in the left inferior cardiac sympathetic nerve. Hypoxia was induced by switching room air to nitrogen/oxygen gas mixture in the inspiratory line reducing end-tidal oxygen from about 18% FETO2 to 10% FETO2 and 6% FETO2 for 60s, respectively. During 6% FETO2 hypoxia, the amplitude of the somato-cardiac sympathetic A-reflex increased significantly to 138 +/- 13% of the control, and that of the C-reflex increased to 186 +/- 18% of the control. During 10% FETO2 hypoxia, the A-reflex increased insignificantly to 117 +/- 8%; the amplitude of the C-reflex was augmented significantly to 149 +/- 11% of the control. Peripheral carotid chemoreceptor denervation abolished the facilitatory effects of systemic hypoxia. It is concluded that carotid chemoreceptor stimulation enhances the responsiveness of somato-cardiac sympathetic excitatory reflexes originating in the hind limb receptors.
    [Abstract] [Full Text] [Related] [New Search]