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  • Title: Intergeniculate leaflet lesion and daily rhythms in food-restricted rats fed during daytime.
    Author: Challet E, Pévet P, Malan A.
    Journal: Neurosci Lett; 1996 Oct 04; 216(3):214-8. PubMed ID: 8897496.
    Abstract:
    In control rats kept under light/dark cycle (LD) and fed during daytime 50% of ad lib food intake, the acrophase of temperature rhythm was 5 h phase-advanced, and plateaued close to the light/dark transition. The nocturnal pattern of locomotor activity rhythm was 6 h phase-advanced. By contrast, in food-restricted rats with electrolytic lesion of intergeniculate leaflet (IGL: IGLX group), there was only a 1 h phase-advance of the acrophase of temperature rhythm. Furthermore, except for a feeding-associated activity, the nocturnal pattern of activity of food-restricted IGLX rats remained unchanged. This demonstrates the involvement of IGL in the phase-advancing properties of a timed caloric restriction in LD.
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