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  • Title: Aminoazoles in heterocyclic synthesis. Synthesis of some new pyrimidobenzimidazoles and pyrazolonopyridines as well as triazolo-, tetrazolo- and pyrazolo-pyrimidines of pharmaceutical interest.
    Author: Kandeel EM, Hammouda M, Metwally MA.
    Journal: Boll Chim Farm; 1996 Apr; 135(4):232-5. PubMed ID: 8913052.
    Abstract:
    The reactivity of 3-cinnamoylindole, 3-cinnamoylantipyrine and 1-(3-methyl-1-phenyl-5-pyrazolon-4 yl)-4-antipyrin-4-yl)-prop-2-ene-1- one(la-c) towards 2-aminobenzimidazole, 3-amino-1,2,4-triazole, 5-aminotetrazole monohydrate, 5-amino-3-phenylpyrazole and 3-amino-1-phenyl-2-pyrazolin-5-one to give the fused heterocycles 2a-c, 4a,b, 5a,b, 8a,b, and 10a-c has been investigated. Structures of the synthesized compounds were confirmed by both the analytical and the spectral data (IR, UV and 1H NMR).
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