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  • Title: [Primary amenorrhoea, hypertension, and hypokalaemia in 17-hydroxylase deficiency, a not uncommon condition (author's transl)].
    Author: de Lange WE, Lappöhn RE, Sluiter WJ, Doorenbos H.
    Journal: Dtsch Med Wochenschr; 1977 Jul 15; 102(28):1024-8. PubMed ID: 891369.
    Abstract:
    Five phenotypic female patients with primary amenorrhoea, mild hypertension, and hypokalaemia are described. The condition originates from 17-hydroxylase deficiency in both adrenals and gonads. Two cases had a XY chromosome pattern, two cases were familial. It is suggested to determine serum potassium in all cases with unexplained primary amenorrhoea.
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