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  • Title: Diaphyseal telangiectatic osteosarcoma as a second tumor after bilateral retinoblastomas.
    Author: Brown MJ, Logan PM, O'Connell JX, Janzen DL, Connell DG.
    Journal: Skeletal Radiol; 1996 Oct; 25(7):685-8. PubMed ID: 8915058.
    Abstract:
    In this report, we describe the clinical, imaging, and pathologic findings in a case of diaphyseal telangiectatic osteosarcoma arising 23 years after successful treatment of bilateral retinoblastomas. To our knowledge, telangiectatic osteosarcoma occurring as a second tumor in this setting, outside the radiation treatment field, has not been previously reported. The association of the RB-1 gene defect with retinoblastomas and other tumors is discussed. Also, the computed tomography and magnetic resonance imaging findings in telangiectatic osteosarcoma are described and discussed.
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