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  • Title: 5-Hydroxytryptamine binding to butanol extracts from myelin fragments.
    Author: Ishitani R, Miyakawa A, Saito R, Iwamoto T.
    Journal: Experientia; 1977 Jul 15; 33(7):932-3. PubMed ID: 891779.
    Abstract:
    The myelin fraction of rat brain stem was treated with butanol-water mixtures, and the extracted proteolipids were separated by Sephadex LH20 column chromatography. 2 peaks of proteolipids eluted in chloroform-methanol 4/1 showed the binding capacity for C14 - 5-HT. This finding suggests the necessity of the more careful investigations for the probability of proteolipids as receptor proteins in the central nervous system.
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