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  • Title: Cirrhotic pleural effusion in the absence of ascites.
    Author: Singer JA, Kaplan MM, Katz RL.
    Journal: Gastroenterology; 1977 Sep; 73(3):575-7. PubMed ID: 892357.
    Abstract:
    A 61-year-old female presented with a right transudative pleural effusion in the absence of ascites and other stigmata of chronic liver disease. A diagnosis of cirrhosis with a secondary hydrothorax was eventually established; however, ascites could never be demonstrated clinically or radiographically until just before her death, when hypertonic saline was administered for symptomatic hyponatremia. Based on the autopsy finding of a 1-mm hole in the right diaphragm and her clinical course, a mechanism for the production of a cirrhotic pleural effusion in the absence of asictes is proposed.
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