These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Effects of the blockade of opioid receptor on defensive reactions elicited by electrical stimulation within the deep layers of the superior colliculus and DPAG.
    Author: Coimbra NC, Eichenberger GC, Gorchinski RT, Maisonnette S.
    Journal: Brain Res; 1996 Oct 14; 736(1-2):348-52. PubMed ID: 8930342.
    Abstract:
    The effects of peripheral administration of naloxone and naltrexone on aversive thresholds (freezing and escape reactions) elicited by electrical stimulation of the midbrain tectum were determined. Naloxone caused a significant increase in the freezing and flight thresholds elicited by electrical stimulation in the deep layers of the superior colliculus and of dorsal regions of the periaqueductal grey matter, as compared with controls. These effects were confirmed by the peripheral administration of naltrexone. These findings suggest that opioid receptors can modulate aversive behaviour elicited by midbrain tectum stimulation.
    [Abstract] [Full Text] [Related] [New Search]