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  • Title: Crohn's disease and acute leukocytoclastic vasculitis of skin.
    Author: Zlatanic J, Fleisher M, Sasson M, Kim P, Korelitz BI.
    Journal: Am J Gastroenterol; 1996 Nov; 91(11):2410-3. PubMed ID: 8931427.
    Abstract:
    A 39-yr-old white male with a prolonged history of Crohn's disease presented with worsening diarrhea associated with an increasingly painful rash of both lower extremities as well as left ankle swelling. A skin biopsy revealed an acute leukocytoclastic vasculitis. Intravenous hydrocortisone followed by oral prednisone achieved a rapid remission of the both cutaneous and gastrointestinal manifestations. Long-term remission has been maintained with 6-mercaptopurine and mesalamine. The rare association between cutaneous vasculitis and Crohn's disease is discussed and earlier reported cases reviewed.
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