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  • Title: Use of the chemical structure of peptides as the starting point to design nonpeptide agonists and antagonists at peptide receptors: examples with cholecystokinin and tachykinins.
    Author: Horwell DC.
    Journal: Bioorg Med Chem; 1996 Oct; 4(10):1573-6. PubMed ID: 8931926.
    Abstract:
    This review summarizes a design strategy to give examples of nonpeptides starting from cholecystokinin (CCK-A and -B) and tachykinins (substance P) (NK-1, -2, -3) as potent functional agonists and antagonists with utility as therapeutic agents.
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