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  • Title: Adjuvant antimicrobial therapy with renal calculus surgery.
    Author: Harrison LH, Whitehurst AW, Boyce WH.
    Journal: J Urol; 1977 Aug; 118(2):233-6. PubMed ID: 894798.
    Abstract:
    A randomized prospective study was done, comparing massive penicillin dosage (60 million units) to the recommended dose of ticarcillin (200 mg. per kg.) in the treatment of complicated urinary tract infections. A total of 50 patients with staghorn or multiple calculi who underwent anatrophic nephrolithotomy was entered into the study during a period of 14 months. Bacteriologic results were comparable. No significant toxicity from either massive penicillin or ticarcillin was observed.
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