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  • Title: Synthesis and biological activities of some new 4,5-dihydro-1H-1,2,4-triazol-5-ones.
    Author: Demirbas A, Johansson CB, Duman N, Ikizler AA.
    Journal: Acta Pol Pharm; 1996; 53(2):117-21. PubMed ID: 8960286.
    Abstract:
    The reactions of 3-alkyl(aryl)-4-phenylamino-4,5-dihydro-1H-1,2,4-triazol-5-ones with appropriate alkyl halides via sodio derivatives were studied and the corresponding 1-alkyl-3-alkyl(aryl)-4-phenylamino-4,5-dihydro-1H-1,2,4-traizol-5 -ones were synthesized. Next, the new compounds were tested for their in vitro antimicrobial activities.
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