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  • Title: [Nucleic acid and protein synthesis in the body of chicks infested by various species of Eimeria].
    Author: Khovanskikh AE, Krylov MV, Mikhaĭlov GA, Mishin VS, Krylova NP.
    Journal: Parazitologiia; 1977; 11(4):353-60. PubMed ID: 896279.
    Abstract:
    The infection of chicks with optimal immunogenic doses of oocysts of E. tenella and E. acervulina results in the activation of biosynthesis of proteins and nucleic acids in the Fabricius bursa, spleen, thymus and blind processes of the intestine. The infection causes the increase in the quantity and synthesis intensity of immunoglobulins G and M that suggests a stimulation of cellular and immunity factors in the ogranism of an immunized bird. Maximum changes in biosynthesis of compounds studied are reported four days after the infection that confirms high immunogenic properties of the second generation schizonts. A study of protein synthesis in limphoid organs of chicks infected only with E. tenella has yielded the same results. The infection with E. acervulina caused but negligible changes in the protein metabolism, i.e. coccidians of E. tenella possess more immunogenic properties.
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