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  • Title: Mechanism of action of hemolysin III from Bacillus cereus.
    Author: Baida GE, Kuzmin NP.
    Journal: Biochim Biophys Acta; 1996 Oct 23; 1284(2):122-4. PubMed ID: 8962879.
    Abstract:
    Bacillus cereus hemolysin III activity was tested in crude extracts, from Escherichia coli carrying the hly-III gene. It was concluded that hemolysin III is a pore-forming hemolysin with functional pore diameter of about 3-3.5 nm. Hemolysis occurs in at least three steps: (i) the temperature-dependent binding of the Hly-III monomers to the erythrocyte membrane; (ii) the temperature-dependent formation of the transmembrane oligomeric pore; (iii) the temperature-independent erythrocyte lysis.
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