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  • Title: Hemolytic anemia provoked by recombinant alpha-interferon.
    Author: Takase K, Nakano T, Hamada M, Shiraki K, Oohashi Y, Kihira T, Tameda Y.
    Journal: J Gastroenterol; 1995 Dec; 30(6):795-7. PubMed ID: 8963402.
    Abstract:
    A 30-year-old female with chronic hepatitis C treated with recombinant alpha-interferon developed serious hemolytic anemia after receiving 10 million units a day for 4 weeks. The results of Coombs' tests were negative before and after interferon therapy. The hemolytic anemia gradually improved after the withdrawal of recombinant alpha-interferon and the administration of methyl-prednisolone. The clinical course suggested that the recombinant alpha-interferon had provoked the hemolytic anemia.
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