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  • Title: [Bovine spongiform encephalopathy. Review of data collected since the statement of February 6, 1996].
    Author: Brugère-Picoux J, Rérat A.
    Journal: Bull Acad Natl Med; 1996 May; 180(5):1007-12; discussion 1012-5. PubMed ID: 8963704.
    Abstract:
    The observation in 1995 and 1996 of 10 cases of a new variant of Creutzfeldt-Jakob disease (V-CJD) in U.K. suggested a possible relation between this human cases and bovine spongiform encephalopathy (BSE). Recent papers about this topic are reviewed : hypothesis of a possible genetic link between man and cattle, hypothesis of a acquired resistance against the agent of BSE after a previous infection by a less virulent agent of ovine origin, importance of polymorphism at codon 129 according to the hypothesis of a virus-induced amyloidosis, diagnostic test with cerebrospinal fluid, epidemiology of BSE and prediction of future BSE spread.
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