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  • Title: An ethidium-induced double helix of poly(dA)-poly(rU).
    Author: Lehrman EA, Crothers DM.
    Journal: Nucleic Acids Res; 1977; 4(5):1381-92. PubMed ID: 896465.
    Abstract:
    Equilibrium dialysis, relaxation kinetic, melting, and continuous variation mixing experiments on complexes of poly(dA) and poly(rU) demonstrate that ethidium induces conversion of a 1:1 mixture of these homopolymers (at one molar salt and 19 degrees C) from a three stranded to a two stranded helix. This is the first demonstration of a double helix of poly(dA)-poly(rU) in solution.
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