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  • Title: Demonstration of frontal hypoperfusion in benign exertional headache by Technetium-99m-HMPAO SPECT.
    Author: Başoglu T, Ozbenli T, Bernay I, Sahin M, Onur A, Demirçali AE, Coşkun C, Onen T.
    Journal: J Nucl Med; 1996 Jul; 37(7):1172-4. PubMed ID: 8965191.
    Abstract:
    We present a case of benign exertional headache (BEH) in a 15-yr-old boy. The patient suffered from exclusively exercise-induced headaches with migraine-like accompanying symptoms. No pathology could be detected by routine cardiovascular or neurological examinations by CT. The postexercise 99mTc-HMPAO brain SPECT performed during the provoked headache attack showed asymmetric bifrontal hypoperfusion. A second 99mTc-HMPAO study during a symptom-free phase under resting conditions was normal. The detection of impaired regional cerebral blood flow (rCBF) by 99mTc-HMPAO brain SPECT indicates a perfusion-related pathology in this type of headache. Analysis of rCBF with 99mTc-HMPAO in larger studies could be helpful in the clarification of BEH pathogenesis.
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