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  • Title: [Short- and long-term evaluation of treatment of critical ischemia of the lower lim with PGE1 (alprostadyl alpha-cyclodestrine)].
    Author: Amitrano M, Izzo M, Castaldo G, Lombardi R, Tizzano R, Bellizzi AM, Vietri GC, Sorrentino A, D'Avanzo A.
    Journal: Minerva Cardioangiol; 1996; 44(7-8):391-6. PubMed ID: 8965998.
    Abstract:
    Twenty-five patients affected by chronic lower limb obliterating arteriopathy with critical ischemia in one limb were treated with PGE1 for 4 weeks and then followed-up for one year. On day 14 of treatment three groups of patients were selected on the basis of clinical symptoms and instrumental tests; patients were subdivided into Responders, Partial Responders and Non-Responders. The results obtained were satisfactory in view of the fact that the selection into three groups enabled Partial Responders to be reclassified, in some cases by repeating the treatment cycle.
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