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  • Title: [Immunological indicators in children with laryngeal papillomatosis and possible ways of immunocorrection].
    Author: Garashchenko TI, Markova TP, Chuvirov DG.
    Journal: Vestn Otorinolaringol; 1996; (4):15-8. PubMed ID: 8966870.
    Abstract:
    Clinicoimmunological characteristics were followed up in the course of laryngeal papillomatosis (LP) in 96 children. It was found that they had suppressed T-cell immunity, phagocytosis which still worsen with the disease aggravation and recurrences. A decrease in nonspecific resistance, properdin, lysozyme, complement and secretory IgA indicated impairment of nasopharyngeal and laryngeal local immunity. A scheme of combined treatment is proposed incorporating basic therapy with reaferon, systemic immunomodulators (thymalin, T-activin) and local immunocorrection. Such approach reduced the time of basic treatment and prolonged remission 2.5-3-fold.
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