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  • Title: The influence of unsaturated fatty acids on prostaglandin-release in isolated perfused guinea-pig hearts.
    Author: Mentz P, Forster W.
    Journal: Prostaglandins; 1977 Jul; 14(1):173-9. PubMed ID: 897212.
    Abstract:
    Isolated perfused hearts of guinea-pig continuously release a prostaglandin-like substance into the effluent. Polyunsaturaed fatty acids, linoleic acid and arachidonic acid greater than linolenic acid, induced an increase in PG-efflux. Oleic acid was without effect. The results suggest that PG-formation is involved in the increase of contractile force and coronary flow after administration of linoleic, linolenic and arachidonic acids.
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