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  • Title: Effect of mianserine on brain serotonin turnover in mice.
    Author: Bhargava HN, Kasabdji D.
    Journal: Res Commun Chem Pathol Pharmacol; 1977 Aug; 17(4):735-8. PubMed ID: 897355.
    Abstract:
    One hr after mianserine administration brain 5-HT concentration was reduced, the greatest decrease was observed with 2.5 mg/kg dose. This reduction lasted for 1 hr. Brain 5-HT turnover was increased by all doses of mianserine used. The increase in brain 5-HT turnover after a single injection lasted for 8 hr. This increase may be related to inhibition of central 5-HT receptors.
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