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  • Title: Localization of Cu/Zn-SOD and Mn-SOD in the rat cochlea.
    Author: Rarey KE, Yao X.
    Journal: Acta Otolaryngol; 1996 Nov; 116(6):833-5. PubMed ID: 8973716.
    Abstract:
    Distributions of the copper/zinc-superoxide dismutase (Cu/Zn-SOD) and the manganese superoxide dismutase (Mn-SOD) in the rat cochlea were studied by immunohistochemistry with specific polyclonal antibodies to Mn-SOD and Cu/Zn-SOD. Coexpression of Mn-SOD and Cu/Zn-SOD was observed in the cochlear tissues with differing immunoactivity intensities. The presence of Cu/Zn- and Mn-SOD implies the existence of a defense system against free oxygen radical (FOR) injury in cochlear tissues.
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