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  • Title: [The effect of benzodiazepine derivatives on the formation of brain edema-swelling in the dynamics of the posttraumatic period].
    Author: Novikov VE.
    Journal: Eksp Klin Farmakol; 1996; 59(3):61-3. PubMed ID: 8974588.
    Abstract:
    In experiments on rats the influence of diazepam, cinazepam, and phenazepam (0.5 mg/kg, intraperitoneally) on the development of brain edema in the dynamics of acute craniocerebral injury was studied. The diazepam and phenazepam prevented the development of brain edema in the post-traumatic period. The antiedematous effect of benzodiazepines was connected with their influence on metabolism of the brain.
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