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  • Title: [Acute interstitial nephropathy induced by vancomycin].
    Author: Azar R, Bakhache E, Boldron A.
    Journal: Nephrologie; 1996; 17(6):327-8. PubMed ID: 8975151.
    Abstract:
    The authors report a case of tubulo-interstitial nephritis with acute renal failure due to vancomycin used to treat a patient with enterococcus endocarditis. Rechallenge with vancomycin several days after stopping the drug resulted in the appearance of a maculopapular rash and rapid onset of acute oligo-anuric renal failure. Renal biopsy revealed acute interstitial nephritis. This feature is suggestive of cellular mediated hypersensitivity.
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