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  • Title: Modulating platelet function with selective thrombin inhibitors.
    Author: Verstraete M.
    Journal: Haemostasis; 1996 Oct; 26 Suppl 4():70-7. PubMed ID: 8979113.
    Abstract:
    In addition to its pivotal role in blood coagulation, thrombin is one of the most important agonists for platelet recruitment and aggregation. Thrombin inhibitors impede thrombin-induced platelet aggregation but have no effect on aggregation induced by other agonists. A review is presented of selective thrombin inhibitors now in clinical investigation, some of which are also orally active.
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