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  • Title: Production of sodium azide inactivating substance by resistant mutants of Salmonella typhimurium and other bacteria.
    Author: Banic S.
    Journal: J Chemother; 1996 Dec; 8(6):432-7. PubMed ID: 8981183.
    Abstract:
    We have found that azide-resistant mutants of Salmonella typhimurium and of other bacteria studied produce a substance which inactivates the azide. The production of this substance was proved by the demonstration of a satellite growth of azide-sensitive cells around colonies of azide-resistant mutants and by testing azide inactivating properties of culture filtrates of the azide-resistant strains. The same substance was found to be present in lower concentrations in culture filtrates of wild-type sensitive strains. In both cultures of sensitive strains, it was apparently produced by the resistant mutants and not by the sensitive cells. The substance does not pass across a dialysis membrane and is heat stable. It has a high molecular weight but is not a protein.
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