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  • Title: Cytotoxic oxygenated desmosterols of the red alga Galaxaura marginata.
    Author: Sheu JH, Huang SY, Duh CY.
    Journal: J Nat Prod; 1996 Jan; 59(1):23-6. PubMed ID: 8984148.
    Abstract:
    Desmosterol (1), 24,25-epoxycholesterol (2), 24-hydroperoxycholesta-5,25-dien-3 beta-ol (3), 25-hydroperoxycholesta-5,23(E)-dien-3 beta-ol (4), cholesta-5,25-diene-3 beta,24-diol (5), and 24,25-epoxy-6 beta-hydroxycholest-4-en-3-one (7) were isolated from the marine red alga Galaxaura marginata; sterols 3, 4, and 7 were isolated for the first time from a natural source. Sterols 3-7 exhibited significant cytotoxicity toward several cancer cell lines.
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