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  • Title: The experience of the "Stefan S. Nicolau" Institue of Virology in the preparation of administration of inactivated influenza vaccines applicable by nasal or oral route.
    Author: Petrescu A, Cajal N, Broniţki A, Mihail A, Teodosiu O, Popescu G, Isaia G, Popescu A.
    Journal: Virologie; 1977; 28(3):213-7. PubMed ID: 898654.
    Abstract:
    Studies conducted for over 20 years allowed the authors to accumulate a rich experience in the production and administration of an inactivated influenza vaccine applicable by nasal and oral route, prepared in the "Stefan S. Nicolau" Institute of Virology. Applied as a monovalent in a single dose of 1000 IU, the vaccine induced seroconversion of 70% of the vaccines and ensured a 2--4-fold decrease in influenza morbidity. Owing to these qualities the vaccine represents one of the most advantageous preparations used in influenza prophylaxis.
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