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  • Title: Antiplatelet arylnaphthalide lignans from Justicia procumbens.
    Author: Chen CC, Hsin WC, Ko FN, Huang YL, Ou JC, Teng CM.
    Journal: J Nat Prod; 1996 Dec; 59(12):1149-50. PubMed ID: 8988600.
    Abstract:
    Fractionation of the EtOH extract of Justicia procumbens, guided by antiplatelet bioassay, led to the isolation of nine known arylnaphthalide lignans, neojusticin A (1), justicidin B (2), justicidin A (3), taiwanin E methyl ether (4), neojusticin B (5), chinensinaphthol methyl ether (6), taiwanin E (8), chinensinaphthol (9), and diphyllin (10), and a new arylnaphthalide lignan that was characterized by spectral means as 4'-demethylchinensinaphthol methyl ether (7). Compounds 1, 2, 4, and 8 significantly inhibited platelet aggregation.
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