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Title: Two new aromatic constitutents from the rootwood of Aeschynomene mimosifolia. Author: Fullas F, Kornberg LJ, Wani MC, Wall ME, Farnsworth NR, Chagwedera TE, Kinghorn AD. Journal: J Nat Prod; 1996 Feb; 59(2):190-2. PubMed ID: 8991952. Abstract: The rootwood of Aeschynomene mimosifolia Vatke (Leguminosae) has yielded a new neoflavonoid, mimosifoliol (1), and an unusual C16-styrylcycloheptenone derivative, mimosifolenone (2). The structures of these compounds were determined on the basis of spectral analysis. Compound 1 demonstrated weak activity in DNA-strand scission assay, while compound 2 was found to be inactive. Mimosifoliol (1) was inactive toward several human cell lines, while 2 was moderately active against the KB cell line.[Abstract] [Full Text] [Related] [New Search]