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  • Title: Osteosarcoma complicating Paget's disease of the spine with neurologic complications.
    Author: Huang TL, Cohen NJ, Sahgal S, Tseng CH.
    Journal: Clin Orthop Relat Res; 1979 Jun; (141):260-5. PubMed ID: 89924.
    Abstract:
    An osteosarcoma with neurologic manifestations complicated Paget's disease of the lumbar spine in a 63-year-old man. Initially without demonstrable metastasis, the patient was treated by decompressive laminectomy followed by radiation and adjuvant chemotherapy (COMPADRI-1 regimen). While such treatment may not be curative, there are significant palliative benefits.
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