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  • Title: FDG-PET evaluation of retroperitoneal metastases of testicular cancer before and after chemotherapy.
    Author: Reinhardt MJ, Müller-Mattheis VG, Gerharz CD, Vosberg HR, Ackermann R, Müller-Gärtner HW.
    Journal: J Nucl Med; 1997 Jan; 38(1):99-101. PubMed ID: 8998160.
    Abstract:
    We describe a patient whose primary tumor was a testicular teratocarcinoma predominantly composed of embryonal carcinoma. Before chemotherapy, the retroperitoneal metastases demonstrated heterogeneous, increased glucose metabolism as measured by 2-[18F]fluoro-2-deoxy-D-glucose and PET (FDG-PET). After chemotherapy, FDG uptake was reduced to normal values despite increased tumor volume. Histology revealed a pure mature teratoma. This observation suggests that further studies are needed to determine whether tumor differentiation of testicular teratocarcinoma metastases can be assessed by measuring glucose metabolism.
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