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  • Title: [Duodenal ulcer: clinical significance of adaptation defects in the system of neurohumoral regulation].
    Author: Eremina EI.
    Journal: Klin Med (Mosk); 1996; 74(4):29-31. PubMed ID: 8999147.
    Abstract:
    Radioimmunoassay was used to determine prostaglandin (PGE-2) and cyclic nucleotides (cAMP and cGMP) concentrations in the serum before, 1 and 2 hours after standard test breakfast (5066 kJ) in 65 patients with duodenal ulcer. Basal hyperproduction of prostaglandins and cyclic nucleotides were interpreted as an adaptation-compensatory mechanism. The unbalance of their aftermeal reactions persistent even in ulcer healing may belong to factors of the disease progression.
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