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  • Title: Strongly reduced phage Qbeta replication, but normal phage MS2 replication in an Escherichia coli K12 mutant with inactivated Qbeta host factor (hfq) gene.
    Author: Su Q, Schuppli D, Tsui HcT, Winkler ME, Weber H.
    Journal: Virology; 1997 Jan 06; 227(1):211-4. PubMed ID: 9007075.
    Abstract:
    RNA phage production was observed in Escherichia coli hfq mutant strains transformed with plasmids containing genomic cDNA of phages Qbeta or MS2. Qbeta production was reduced 5000-fold in an insertional mutant containing an omega cassette in the middle of hfq, but was unaffected in a mutant with the cassette near the end of hfq. The insertions had no effect on MS2 replication.
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