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  • Title: Toxicity of selected antibiotics in vitreous replacement fluid.
    Author: Stainer GA, Peyman GA, Meisels H, Fishman G.
    Journal: Ann Ophthalmol; 1977 May; 9(5):615-8. PubMed ID: 900711.
    Abstract:
    Experiments with rabbits demonstrated no toxic effects on the retina after vitrectomy when the infusion fluid contained either 20 microgram/ml chloramphenicol saline, 10 microgram/ml amikacin saline, 10 microgram/ml tobramycin saline, or 10 microgram/ml clindamycin saline. We found abnormal electroretinograms and abnormal histologic findings in eyes receiving vitreous replacement with these same drugs in higher concentrations.
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